Abstract Search

ea0090p566 | Adrenal and Cardiovascular Endocrinology | ECE2023

Evaluation of CYP11B2 immunostaining findings and cure rates of primary aldosteronism subtyped by anatomical imaging and functional methods

Viukari Marianna , Leijon Helena , Vesterinen Tiina , Porsti Ilkka , Nevalainen Pasi I. , Matikainen Niina

Background: The best lateralization method to ascertain cure after surgery in unilateral primary aldosteronism (PA) is debated. Risk of persistent of PA in those with non-classical adrenal histopathology remains poorly characterized.Objective: We examined the value of anatomical compared with functional subtyping and the significance of immunohistochemical analysis of CYP11B1 and CYP11B2 for the outcome and histopathological diagnosis of primary aldoster...

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ea0063gp195 | Adrenal and Neuroendocrine - Clinical | ECE2019

Evaluation of clinical and biochemical cure and adrenal CYP11B2 and CYP11B1 immunostaining in primary aldosteronism operated after adrenal venous sampling

Matikainen Niina , Nevalainen Pasi I , Soinio Minna , Gomez-Sanchez Celso , Vesterinen Tiina , Leijon Helena

Background: The cure of unilateral primary aldosteronism (PA) after adrenalectomy can result in complete, partial or absent biochemical and clinical improvement1. Histological findings from HE samples are of little assistance in determining if adenoma or hyperplastic adrenal tissue is hormonally overactive. Our aim in the present study was to compare immunohistochemical (IHC) CYP11B1 and CYP11B2 staining in adrenal slices to histological diagnosis based on H&E s...

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Endocrine Abstracts

Evaluation of CYP11B2 immunostaining findings and cure rates of primary aldosteronism subtyped by anatomical imaging and functional methods

Evaluation of clinical and biochemical cure and adrenal CYP11B2 and CYP11B1 immunostaining in primary aldosteronism operated after adrenal venous sampling

BiosciAbstracts